OsteoBites

May 8, 2025

A Guide to the FACTOR 2025 Scientific Panels with Matteo Trucco, MD

April 24, 2025

Autologous Cancer Vaccine with Checkpoint Inhibitor for Treatment of Canine Osteosarcoma

April 10, 2025

La Cirugía de Salvamento de Extremidades

April 3, 2025

Advocating for Cures: How You Can Support the Give Kids a Chance Act and Advance Pediatric Cancer Research

March 27, 2025

Tumor cGAS-STING Repression Drives Immune Evasion in Osteosarcoma and is Therapeutically Targetable via Host STING Activation

March 13, 2025

Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition

March 6, 2025

Pharmacologic Inhibition of EIF4A Blocks NRF2 Synthesis to Prevent Osteosarcoma Metastasis

February 27, 2025

Multi-Modal Omics Analysis Identifies Targetable Sensory Neuron Circuitry that Promotes Sarcoma Disease Progression

February 13, 2025

An Organoid-Based Functional Precision Medicine Trial in Osteosarcoma (PREMOST)

February 6, 2025

Minimally Invasive Metastasectomy in Canines (MIMIC)

January 23, 2025

Live-Cell Whole Tissue Models Reveal Sources of Dynamic Signaling Heterogeneity and Single Cell Drug Response Variation in the Metastatic Niche

January 9, 2025

COG Blueprint for Research on Bone Tumors

December 12, 2024

Understanding Tumor Evolution in Osteosarcoma

December 5, 2024

Macrophage Engineered Vesicles to Treat Pediatric Osteosarcoma

November 7, 2024

Repurposing Virus Specific T cells as Immune Therapy for Osteosarcoma

October 31, 2024

Repurposing Drugs for Osteosarcoma

October 24, 2024

The Ablative and Immunomodulatory Effects of Histotripsy Treatment in Osteosarcoma

September 26, 2024

Molecular and Cellular Deconstruction of Metastatic Osteosarcoma

August 29, 2024

Fit for Filing Academic Clinical Trials: An Industry Perspective

August 22, 2024

Magnetic Resonance Guided (MRg) High Intensity Focused Ultrasound (HIFU) For Palliation of Canine Appendicular Osteosarcoma

August 8, 2024

Clinical Utility of Functional Precision Medicine to Guide Treatments for Osteosarcoma Patients

August 1, 2024

Immune Determinants of CAR-T Cell Expansion in Solid Tumor Patients Receiving GD2 CAR-T Cell Therapy

July 25, 2024

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination with Gemcitabine and Docetaxel in Patients with Relapsed or Refractory Pediatric Bone and Soft Tissue (TINKS)

July 11, 2024

Genomes, Avatars and AI: The Future of Personalized Medicine

May 30, 2024

Exploring Novel Immunotherapies for Canine Osteosarcoma

May 23, 2024

A Guide to the FACTOR 2024 Scientific Panels with Matteo Trucco, MD

May 9, 2024

Creating a Translational Genomic Framework for Canine Osteosarcoma: Updates on the NCI DOG2 Project

May 2, 2024

Positioning Poly-(ADP)-Ribose Polymerase Inhibitors (PARPi) for the Treatment of Osteosarcoma

April 25, 2024

TGF-Beta Inhibition as a Novel Therapeutic Option in Osteosarcoma

April 11, 2024

Phase 1 Study of Cabozantinib in Combination with Topotecan-Cyclophosphamide for Patients with Relapsed or Refractory Ewing Sarcoma or Osteosarcoma

April 4, 2024

Targeting Urea Cycle Dysfunction to Prevent and Treat Osteosarcoma Metastasis

March 14, 2024

Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research

March 7, 2024

Patient Perspectives on Participating in Research and Clinical Trials

February 29, 2024

Tissue Engineering Strategies for Elucidating OS Biology and Drug Discovery

February 22, 2024

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic and Response Diagnostic: The LEOPARD Study

February 8, 2024

Prevention of Cisplatin-Induced Hearing Loss: Implications for Young People Treated for Osteosarcoma

January 25, 2024

TACOS: A Phase 2 Trial of Atezolizumab and Cabozantinib in Osteosarcoma

January 11, 2024

Interventions to Promote Physical Function During and After Treatment for Osteosarcoma

December 14, 2023

The Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan (CAUSAL) study

December 7, 2023

Developing a Multiscale Transcriptional Atlas of Sarcoma

November 30, 2023

Immunological Mechanisms of Cancer Defense

November 2, 2023

An Overview of the 2023-2024 OutSmarting Osteosarcoma Research Grant Program

October 26, 2023

Cabozantinib as a Maintenance Therapy to Prevent Recurrence of High-Risk Pediatric Solid Tumors

October 12, 2023

Preguntas y Respuestas con Nino Rainusso, MD

October 5, 2023

TCF-001 TRACK (Target Rare Cancer Knowledge): A Clinical Trial Studying Precision Medicine in Rare Cancers

September 28, 2023

Repurposing Disulfiram to Overcome Chemotherapy Resistance in Relapsed Sarcomas

September 14, 2023

Addressing the Unmet Scientific Challenges in Osteosarcoma Treatment through Innovative Engineering Techniques

August 31, 2023

Implementing Multi-Targeted Tyrosine Kinase Inhibitors in Combination with Chemotherapy for Osteosarcoma

August 24, 2023

Immune Therapies in EGFR-Expressing Cancers

August 10, 2023

Treatment of Osteosarcoma Using Smart Targeted Drug Delivery Nanoplatforms

August 3, 2023

MIB Agents and SARC: A Case Study in Collaboration

July 27, 2023

OSI Funded Work

July 13, 2023

Pretargeted Approach to Delivery of Radiopharmaceutical Therapy for Bone Cancer - A Click Chemistry Study in Canines with Osteosarcoma

June 8, 2023

The Importance of Osteosarcoma Research: Count Me In's Patient Powered Osteosarcoma Project (OSProject.org)

June 1, 2023

Osteosarcoma Organoid Models: the Potential and Limitations of Personalized Avatars

May 25, 2023

Reprogramming NK Cells Within the Tumor Microenvironment of Osteosarcoma Lung Metastases

May 11, 2023

OSI Connect: Osteosarcoma Answers and Assistance

May 4, 2023

Phase 1 Trial with GD2-SADA:177Lu-DOTA Drug Complex in Patients with Recurrent or Refractory Metastatic Solid Tumors Known to Express GD2

April 27, 2023

SCF-Skp2 Protein Complex as a Therapy for Osteosarcoma by Blocking the Mutational Effects of Rb and p53

April 13, 2023

Cold Atmospheric Plasma: A New Therapeutical Option for Osteosarcoma?

March 30, 2023

UHRF1 Overexpression Promotes Osteosarcoma Metastasis Through Altered Exosome Production and AMPK/SEMA3E Suppression

March 23, 2023

SBRT and SRS for Sarcoma

March 9, 2023

Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks

March 2, 2023

SarcoSIGHT – A Randomised Controlled Trial of Fluorescence Guided Sarcoma Surgery Versus Standard of Care

February 16, 2023

Virtual Surgical Planning and 3D Printing in Pediatric Musculoskeletal Oncological Resections

January 26, 2023

Two epigenetically distinct cellular states in osteosarcoma are regulated by a state-specific set of transcription factors driving differential drug response

January 12, 2023

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

December 8, 2022

Cell based therapies for osteosarcoma

November 10, 2022

Interventional Radiology/HIFU perspectives for osteosarcoma

November 3, 2022

Focal Adhesion Kinase (FAK) inhibition to improve losartan-sunitinib immunotherapy in metastatic osteosarcoma

October 27, 2022

Updates from clinical sequencing of 2,138 bone and soft tissue sarcomas

October 20, 2022

osTEAo: Halloween Spooky Stories

October 13, 2022

How Osteosarcoma Evolves from Diagnosis to Relapse

October 6, 2022

Transforming the Way Researchers Share Data: Lessons from the Pediatric Cancer Data Commons

September 22, 2022

OsTEAo: Dating & Intimacy with Lauren Broschak, MSW, LCSW, OSW-C

September 15, 2022

Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma

September 8, 2022

A report on the phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma

September 1, 2022

Inhaled recombinant human IL-15 in dogs with naturally occurring pulmonary metastases from osteosarcoma or melanoma: a phase 1 study of clinical activity and correlates of response

August 25, 2022

Outsmarting OS 2021 Funded Research Update: Exploring Aldehyde Dehydrogenase and Androgen Receptor Actions to OutSmart Osteosarcoma Metastases

August 18, 2022

OsTEAo: Back To School

August 11, 2022

Combination Therapies to Improve Immune-Mediated Approaches for Osteosarcoma

August 4, 2022

Using RNA-nanoparticle vaccines to overcome the immunosuppressive tumor microenvironment of canine osteosarcoma

July 28, 2022

COG Project: Every Child

July 14, 2022

Unanswered Clinical Questions in Sarcoma: Opportunities to move from bedside to bench

July 7, 2022

Molecular Profiling Identifies Targeted Therapy Opportunities in Pediatric Solid Cancer

June 16, 2022

Navigating Pediatric Cancer Clinical Trials

June 9, 2022

Update on OSI funded phase 2 Trial of Olaparib + Ceralasertib in Recurrent Osteosarcoma

May 26, 2022

Limb Salvage Surgery for OS: Patient & Surgeon Perspectives

May 19, 2022

"Armored" CAR T cells for Osteosarcoma

May 12, 2022

Immunotherapy for Osteosarcoma - Where do we go from here?

May 5, 2022

The Osteosarcoma Project

April 28, 2022

OsTEAo: Spilling The Tea On Osteosarcoma

April 21, 2022

Update on Clinical Trial Development Targeting Tumor Microenvironment in Refractory and Metastatic Osteosarcoma

April 14, 2022

https://anchor.fm/mibagents

Exploring the Use of a Predictive Tool for Methotrexate Clearance

April 7, 2022

A Phase 1/2 Study of ZN-c3 Plus Gemcitabine in Relapsed or Refractory Osteosarcoma

March 31, 2022

MYC Amplification As a Prognostic Biomarker in Osteosarcoma

March 24, 2022

Compassionate Use of Investigational Drugs: A Strategy to Access Unapproved Therapies for Pediatric Oncology Patients.

March 17, 2022

The Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) International Randomized Controlled Trial

March 10, 2022

Osteosarcoma Q&A

March 3, 2022

Truths & Myths of Nutrition in Cancer